Monday, February 27, 2012

SEVEN Black Tie Event For Life Science CEOs, Entrepreneurs, Professionals & Investors


SEVEN (Scientific Entrepreneur & Venture Capital Network) Orange County is hosting a Life Science Executive Mixer.- Join on Linkedin SEVEN

 
The event is a black tie cocktail event starting at 5:30 PM to 9:00PM.
Date: 24 May 2012
Location: Pacific Club in Newport Beach
Registration: Pl contact Raj at : accessclinicaltrials@gmail.com

Sponsors: Pl contact : Raj at: accessclinicaltrials@gmail.com
There is opportunity to sponsor the event. pl call: 714-658-3039






This event will bring the medical device, pharma, biotech and health care IT entrepreneurs, executives and the investor community together to boost the booming life science industry in Orange County and So Cal.

About 200 Life Science executives, investors and start up entrepreneurs are expected to attend.

SEVEN is screening Medical Device, Biotech, Healthcare IT start up companies that would like to have a table top display/presentation (limited to 20 tabletops only) for an exclusive CEO/Investor Black Tie Event for Life Science companies, pl note few spots are left.  Pl Email to qualify for the event. (Start up with innovative technology, good team, good story)

Orange County, California is one of the hotbeds of innovation in the med-tech sector. OC the region of Southern California mostly known for postcard-pretty beaches, tourist attractions and the TV shows. OC is a lot more than the fun in the sun, it has served as a incubator for the best medical technologies in the medical device space.
OC is a hub for IP and corporate attorneys who have had tremendous success in harnessing the IP and M&A deals for the young startups. So Cal is hoping to see the influx of venture capitalist in the region.
We have seen an increase number of medical technologies in the life science space in the So Cal region including Irvine, San Diego, South Orange County and Los Angeles.

Pl send your company profile and executive summary to: Raj Nihalani
E: accessclinicaltrials@gmail.com
For Registration/attendance pl contact:  accessclinicaltrials@gmail.com
There is opportunity to sponsor the event. pl call: 714-658-3039

Friday, February 24, 2012

SEVEN: Black Tie Event for Life Science Entrepreneurs & Investors

SEVEN (Scientific Entrepreneur & Venture Capital Network) Orange County is hosting a Life Science Executive Mixer.- Join on Linkedin SEVEN
 
The event is a black tie cocktail event starting at 5:30 PM to 9:00PM.
Date: 24 May 2012
Location: Irvine/Newport Beach
Registration: Pl contact Raj at : accessclinicaltrials@gmail.com

Sponsors: Pl contact : Raj at: accessclinicaltrials@gmail.com
There is opportunity to sponsor the event. pl call: 714-658-3039

This event will bring the medical device, pharma, biotech and health care IT entrepreneurs, executives and the investor community together to boost the booming life science industry in Orange County and So Cal.

About 200 Life Science executives, investors and start up entrepreneurs are expected to attend.

SEVEN is screening Medical Device, Biotech, Healthcare IT start up companies that would like to have a table top display/presentation (limited to 20 tabletops only) for an exclusive CEO/Investor Black Tie Event for Life Science companies, pl note few spots are left.  Pl Email to qualify for the event. (Start up with innovative technology, good team, good story)

Pl send your company profile and executive summary to: Raj Nihalani
E: accessclinicaltrials@gmail.com
For Registration/attendance pl contact:  accessclinicaltrials@gmail.com
There is opportunity to sponsor the event. pl call: 714-658-3039

Tuesday, February 21, 2012

Health Care and Medical Device Market Predicted to be over $500B

Private investor are jumping in to invest in Medical Device industry as it heats up for a health care boom in Asia by 2015. 
The increasing incidence of chronic diseases such as Obesity,  diabetes, cardiovascular disease, chronic wounds, immobility, pulmonary and vascular diseases is enhancing the need for patient care in hospitals, homes and other care facilities, thereby contributing to the demand for medical devices and diagnostics that are capable of enhancing the overall quality of life. The US leads the high-technology medical devices market, but faces fierce competition from emerging economies. Despite being way behind the US in terms of expertise or innovation, these countries compete on basis of production of low cost medical devices. Demand for medical devices in developing countries, especially China and India, is expected to grow at a faster rate than developed countries owing to factors such as rising disposable incomes, increase in patient population, growing waist lines, obesity on the rise and both India and China face an epidemic of diabetes and obeisty. Australia UK , US, Canada and Mexico are already declared an Obesity epidemic. The obesity device market will be the biggest in the healthcare sector.
Asia is seeing increasing healthcare awareness, improvements in healthcare infrastructure and increase in healthcare spending . In majority of the Asian, Latin America and the Middle East countries, government efforts are focused on improving healthcare services and infrastructure facilities, which is expected to fuel the demand for medical equipment in the next 3 years.

The medical device industry has not been totally insulated from the adverse economic conditions, as evident by the decline in admissions across healthcare facilities and hospitals. Owing to the high levels of unemployment, elective, orthopedic, and cosmetic procedures witnessed a significant decline, thereby affecting profitability of hospitals. Additionally, rising capital costs, declining patient volumes, and unfavorable reimbursement scenario affected revenue generation. With most surgical systems and equipment being capital heavy investments, tight liquidity, lack of credit availability, capital shortages, and high borrowing rates, triggered by the recession, forced hospitals and healthcare facilities to reduce capital expenditures on new equipment. Though developed countries such as North America, Japan and Western and Northern Europe witnessed subdued spending on healthcare services, level of healthcare expenditure in developing markets continued to increase thereby fuelling the demand for medical technologies, products and services. However, mounting healthcare expenditure presents a considerable challenge for most countries, particularly in developed countries that are already grappling with the volatile economic environment.
India and china face a problem of metabolic disease. Which is a mix of hypertention, heart disease and diabetes. The smokers in the region have increased the incidence of tobacco related problems.
Coronary stent shown below is one medical device that is implanted every 20 seconds in Asia.
There is a increased demand in consumables in the medical device sector. Implantables like the lap band will grow in Asia.
Technologies in orthopedics and spine are in great demand. Larger companies cannot compete with small and nimble manufacturers.
Spine surgery is reverting to posterior open repairs due to slower adoption of minimally invasive surgery. The outcomes show little difference between the traditional posterior fixation and minimally invasive surgery. It will take a decade for new technologies to be adopted.

Increase number of private investors are jumping into the space because the institutional investors have not raised new money to invest in early stage technologies.
 Private investors did not have this opportunity until recently.
Private and angel investors understand its a high risk high gain opportunity, accredited investors can take advantage and invest in companies in the seed stage and series A. After Series A  the institutional investors and venture capitalist jump in. Many of the private investors have potential to gain if the company exits in 4-5 years, which can be by virtue of M&A or IPO.

Monday, February 13, 2012

Med Device , Pharma, Biotech & Health Care IT Start up and Executives Mixer, Newport Beach. California

SEVEN (Scientific Entrepreneur & Venture Capital Network) Orange County is hosting a Life Science Executive Mixer.- Join on Linkedin.SEVEN
 
The event is a black tie cocktail event starting at 5:30 PM to 9:00PM.
Date: 26 April 2012
Location: Irvine/Newport Beach
Sponsors: Pl contact : Raj at: accessclinicaltrials@gmail.com
or
Raj@trialmed.com
There is opportunity to sponsor the event. pl call: 714-658-3039


This event will bring the medical device, pharma, biotech and health care IT entrepreneurs, executives and the investor community together to boost the booming life science industry in Orange County and So Cal.
About 200 Life Science executives, investors and start up entrepreneurs are expected to attend.


SEVEN is screening Medical Device, Biotech, Healthcare IT start up companies that would like to have a table top display/presentation (limited to 20 tabletops only) for an exclusive CEO/Investor Black Tie Event for Life Science companies, pl note few spots are left.  Pl Email to qualify for the event. (Start up with innovative technology, good team, good story)

Pl send your company profile and executive summary to: Raj Nihalani
E: accessclinicaltrials@gmail.com
For Registration/attendance pl contact:  accessclinicaltrials@gmail.com
There is opportunity to sponsor the event. pl call: 714-658-3039

Sunday, February 12, 2012

Key to Medical Technology Boom

Continued years of strong and steady growth, the medical technology industry is facing a wave of pressure that is forcing companies in the industry to re-examine the fundamentals of how they compete. The traditional medical technology model that is purely focused on product innovation will not be a the only play in the future. Instead, high performance in the medical technology industry will stem from the ability to develop cost-effective solutions driven by the change in buyers that deliver demonstrable improvements in health outcomes.
Example; Spinofix, Inc is a Irvine, CA based spine technology, is working on a low cost option in the posterior spine fixation technology, it has a unique cross connector system that replaces the spinous process that is dissected out during the spine laminectomy procedure to decompress the spinal cord and the nerves. The technology is fresh, low cost and can impact health outcomes. The company is poised to play a big role in the US and OUS (Outside US) spine market.

Undoubtedly, the changes medical technology companies make will be the key contributor to the med tech boom worldwide and the booming M&A market;
Medical technology companies however, will need to transform their business models to meet the changing demands of health care systems globally. They must carefully choose where to focus their energies both in terms of product and markets. Medical technology companies then must align the right capabilities, innovation models and partnerships that will unlock future growth in these market areas. As a result there is an increase in M&A activity in the medical device sector. Companies are more cash positive than ever, so buying capacity has increased at a decent valuations. US acquirers have to compete with international pharma companies for acquisition of domestic companies.

Monday, February 6, 2012

SEVEN: Scientific Entrepreneur & Venture Capital Network Orange County

SEVEN (Scientific Entrepreneur & Venture Capital Network) Orange County is hosting a Life Science Executive Mixer.- Join on Linkedin.SEVEN
 
The event is a black tie cocktail event starting at 5:30 PM to 9:00PM.
Date: 24 May 2012
Location: Irvine/Newport Beach
Sponsors: Pl contact : Raj at: accessclinicaltrials@gmail.com
There is opportunity to sponsor the event. pl call: 714-658-3039


This event will bring the medical device, pharma, biotech and health care IT entrepreneurs, executives and the investor community together to boost the booming life science industry in Orange County and So Cal.
About 200 Life Science executives, investors and start up entrepreneurs are expected to attend.

SEVEN is screening Medical Device, Biotech, Healthcare IT start up companies that would like to have a table top display/presentation (limited to 20 tabletops only) for an exclusive CEO/Investor Black Tie Event for Life Science companies, pl note few spots are left.  Pl Email to qualify for the event. (Start up with innovative technology, good team, good story)

Pl send your company profile and executive summary to: Raj Nihalani
E: accessclinicaltrials@gmail.com
For Registration/attendance pl contact:  accessclinicaltrials@gmail.com
There is opportunity to sponsor the event. pl call: 714-658-3039


Saturday, February 4, 2012

China Life Science Innovation Occuring Via Investments in Early Stage Companies & M&A

China investing in obesity, diabetes, orthopedics, cardiovasular and generic pharmaceutical and medical device technologies. More Chinese VCs are taking advantage of US based startups in the medical device & pharmacutical startups.
US based VCs are now raising new funds, in the past 3 years they have not raised funds (2009-2011) and are unable to invest in companies that are early stage. China is taking full advantage of novel medtech companies focused on chronic diseases like cardiovascular, diabetes, and newer unmet needs like obesity.
Even countries like India, Taiwan are exploring the opportunity to fund US based start ups. Taiwan just created a Supra Incubation Project to promote life sciences. This effort is an indicator that the life science sector is going to boom in Asia and the effects will trickle to the west and result in a worldwide boom in the life science industry.
 
The potential for China’s medical device, pharmaceutical industry stands out among emerging market peers as pharmaceutical companies contrast the fast growing China market with slightly slow growth in Europe and North America. Unique among the BRIC markets, the Chinese govt announced a US$124 Billion in healthcare stimulus to offer health insurance to over 90% of the Chinese population by 2011, fueling China’s pharmaceutical and medical device market to become the 3rd largest in the world by 2012.

China has some unmet clinical needs. For example, China represents nearly 50% of liver cancer cases in the world.  China’s one child policy has led to children who are now overweight and fighting obesity. The new prosperity along with the western diet is making the children and adults obese. China is seeing the fastest obesity rates. With obesity come problems like diabetes, spine and joint problems. India and China will be the capital of diabetes in the world. 


China lacks: Innovation
The infrastructure is starting to get in place, but to start innovating will take many years. US is already ahead due to investments in the education and R&D infrastructure and experience. However, China can invest and buy innovative companies and compete with US based companies. 



 

Life Science industry poised for a boom in China and the other BRIC countries. US investors may lose the opportunity to invest in early stage companies in the US. Chinese investors may invest in these companies all the way to exit or IPO (which could be listed in the US or China). Recently, Boston based GI Dynamics went public on the Australian stock exchange. The world is indeed flat. Life Science Innovators have more choices now than ever.


Top Sector for Innovation: Life Sciences





Lost in the midst of the seemingly endless headlines of Facebook  IPO and the disasters of the recession, is the fact that today is a time of great innovation with medical products, technology, and entertainment that would have been simply unimaginable in any other time. And the innovations of recent decades are poised to continue helping to reshape our lives to be more productive, healthy, and entertaining.

Every day it seems, headlines remind us that the astronomical costs of health care are snowballing. But however daunting this environment may be, Investors  believe it also provides tremendous opportunities, thanks to a steady stream of new discoveries and groundbreaking practices. Innovation in biotech, medtech, and health care IT [information technology] that can improve the delivery and quality of health care, as well as curtail overall expenses. Eg: Spinofix, Inc is working on next generation spine technology. Onciomed, Inc is another technology that is addressing the $200 Billion obesity, weight loss and diabetes market.

The scientific community continues to make exciting strides in understanding the human genome groundbreaking research that may change our comprehension of human biology and the future course of medicine. Simply put, we’re going through a biological revolution the likes of which we haven’t seen in a generation. Nanotechnology is already playing a role in cosmetics, and beauty creams, lotions. The entire biotechnology sector is going to lead to better drug discovery and, ultimately, much more personalized medicine. The treatment paradigms could shift to pinpoint each patient, as opposed to a subset of patients with a shared illness. In other words, the treatment could be unique and special to each patient.


As life sciences takes a unique turn in this decade, this sector of medical devices, biotech, health care IT has the potential to lead the next economic boom.

Join SCIENTIFIC ENTREPRENEUR & VENTURE CAPITAL NETWORK  on LINKEDIN




Friday, February 3, 2012

Best Sector to Invest: Medical Device S&P benchmark with S&P 500

Medical Device Industry also known as the healthcare equipment and diagnostic companies have shown tremendous resistance to the recession. Many venture capitalist have not raised funds since 2008 and are not investing in the early stage companies, this give the opportunity to private investors to jump in. This opportunity did not exist earlier. In 2012, VCs have started raising new funds to invest in life science companies. The funds will take 12-15 months to raise, this gives the private investors additional time and opportunity to invest in innovative technologies.
The demand of medical product is increasing worldwide. It appears 2015 will see a medical and life sciences boom.

















The above charts speak for itself.
Growth and value investors can find investing in medical equipment companies lucrative.  
With the Aging Population many countries are experiencing an aging population. This growing segment of the population is a positive influence on the future performance of medical equipment companies. Essentially, the rising tide of an aging population helps all the medical equipment companies grow.
The medical equipment sector is well positioned to take advantage of a growing demand for healthcare if the elderly become a larger percentage of the overall population. Moreover, innovations offer ways to improve the lives and welfare of everyone. The best time to buy depends on the type of investor you are. Growth investors can take advantage of the rapid innovation that many companies can accomplish.






Warren Buffet Rules Application to Med-Tech Startup

No. 1:  REINVEST YOUR PROFITS – When you first make money, you may be tempted to spend it.  Don’t.  Instead, reinvest the profits.  Buffett learned this early on. In high school, he and a pal bought a pinball machine to put in a barbershop. With the money they earned, they bought more machines until they had eight in different shops. When the friends sold the venture, Buffett used the proceeds to buy stocks and to start another business.

 Many medical and life science technologies are R&D based. So if you sell your company, re invest in a new venture. Don't blow it!

No. 2:  BE WILLING TO BE DIFFERENT - Don’t base your decisions upon what everyone is saying or doing. When Buffett began managing money in 1956 with $100,000 cobbled together from a handful of investors, he was dubbed an oddball. He worked in Omaha, not on Wall Street, and he refused to tell his partners where he was putting their money. People predicted that he’d fall, but when he closed his partnership 14 years later, it was worth more than $100 million.

You will come across investors and companies looking at your technology and might say, " your technology is not a fit or does not attract us" you pursue your technology,  make sure you are realistic about the growth and outcome of the company. If one investor rejects it, another will see value, nobody knows! better Eg; Facebook. 


No. 3:  NEVER SUCK YOUR THUMBGather in advance any information you need to make a decision, and ask a friend or relative to make sure that you stick to a deadline. Buffett prides himself on swiftly making up his mind and acting on it. He calls any unnecessary sitting and thinking “thumb-sucking.”

Sometimes in the medtech sector the outcomes depend on the user too. Have they followed your instruction to use the medical device or product, was the patient qualified to get your treatment, did you provide adequate training...all this consumes time, Don't make hasty decisions,  take a break and get back at it! harder and more tactfully, this time with a new strategy.

No. 4:  SPELL OUT THE DEAL BEFORE YOU START - Your bargaining leverage is always greatest before you begin a job – that’s when you have something to offer that the other party wants. Buffett learned

this lesson the hard way as a kid, when his grandfather Earnest hired him and a friend to dig out the family grocery store after a blizzard. The boys spent five hours shoveling until they could barely straighten their frozen hands. Afterward, his grandfather gave the pair less that 90 cents to split.

As a life science entrepreneur, your bargaining starts with the investors and ends with the acquirer. So be on your toes! learn ..learn ...learn

No. 5:  WATCH SMALL EXPENSES - Buffett invests in business run by managers who obsess over the tiniest costs. He once acquired a company whose owner counted the sheets in rolls of 500-sheet toilet paper to see if he was being cheated (he was). He also admired a friend who painted only the side of his office building that faced the road.

Many startups make a mistake of spending. I think after the recent recession, lessons have been learned.

No. 6:  LIMIT WHAT YOU BORROW - Buffett has never borrowed a significant amount – not to invest, not for a mortgage. He has gotten many heartrending letters from people who thought their borrowing was manageable but became overwhelmed by debt. His advice: Negotiate with creditors to pay what you can. Then, when you’re debt-free, work on saving some money that you can invest.

In a life science company, debt free is better.

No. 7:  BE PERSISTENT - With tenacity and ingenuity, you can win against a more established competitor. Buffett acquired the Nebraska Furniture Mart in 1983 because he liked the way its founder, Rose Blumkin, did business. A Russian immigrant, she built the mart from a pawnshop into the largest furniture store in North America. Her strategy was to undersell the big shots, and she was a merciless negotiator.

#1 Rule of the game. Be Patient! Persistent & Passionate: Everything takes time.


No. 8:  KNOW WHEN TO QUIT - Once, when Buffett was a teen, he went to the racetrack. He bet on a race and lost. To recoup his funds, he bet on another race. He lost again, leaving him with close to nothing. He felt sick – he had squandered nearly a week’s earnings. Buffett never repeated that mistake.

I think Buffent meant "don't gamble". If you have the right recipe, give it your best shot, in life sciences, the patient outcomes will direct you to quit or stay in the game, don't quit too early. You might be able to change the game with small modifications to your technology.

No. 9:  ASSESS THE RISKS - In 1995, the employer of Buffett’s son, Howie, was accused by the FBI of price-fixing. Buffett advised Howie to imagine the worst- and best-case scenarios if he stayed with the company. His son quickly realized the risks of staying far outweighed any potential gains, and he quit the next day.

As a life science entrepreneur, you know better the risk and benefits of the product and the risk and benefit of sticking around and building value. 

No. 10:  KNOW WHAT SUCCESS REALLY MEANS - Despite his wealth, Buffett does not measure success by dollars. In 2006, he pledged to give away almost his entire fortune to charities, primarily the Bill and Melinda Gates Foundation. He’s adamant about not funding monuments to himself – no Warren Buffett buildings or halls. “When you get to my age, you’ll measure your success in life by how many of the people you want to have love you actually do love you. That’s the ultimate test of how you lived your life.”

 Success is not about winning or losing, its how you played the game.!

Medical technology is booming world wide, sometimes funding the company is challenging, cast a wider net, you will prevail! have faith, believe in yourself, and believe in the technology you created or represent, be real with your team, keep them engaged and treat them like family. Once the life science boom occurs in a couple of years, the valuations of the company will be all time high and all parties involved with the company will be rewarded.